{"id":36134,"date":"2022-01-28T07:18:51","date_gmt":"2022-01-28T10:18:51","guid":{"rendered":"http:\/\/www.radiohorizonte.fm\/radio\/?p=36134"},"modified":"2022-01-28T07:18:51","modified_gmt":"2022-01-28T10:18:51","slug":"prueban-en-humanos-una-vacuna-contra-el-vih","status":"publish","type":"post","link":"http:\/\/www.radiohorizonte.fm\/radio\/2022\/01\/28\/prueban-en-humanos-una-vacuna-contra-el-vih\/","title":{"rendered":"Prueban en humanos una vacuna contra el VIH"},"content":{"rendered":"<p>El ensayo busca estimular la producci\u00f3n de un determinado tipo de anticuerpos (bnAb), capaces de actuar contra las numerosas variantes circulantes del virus.\u00a0El reciente \u00e9xito de la tecnolog\u00eda de ARN mensajero en la lucha contra el Covid-19 en tiempo r\u00e9cord suscit\u00f3 esperanzas, aunque en cuatro d\u00e9cadas de investigaci\u00f3n no se haya logrado a\u00fan una vacuna contra esta enfermedad.<\/p>\n<p><img loading=\"lazy\" decoding=\"async\" class=\"alignnone size-full wp-image-36135\" src=\"http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900.jpg\" alt=\"\" width=\"900\" height=\"506\" srcset=\"http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900.jpg 900w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-300x169.jpg 300w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-768x432.jpg 768w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-65x37.jpg 65w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-320x180.jpg 320w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-85x48.jpg 85w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-220x125.jpg 220w, http:\/\/www.radiohorizonte.fm\/radio\/wp-content\/uploads\/2022\/01\/5a203d501aca4_900-90x51.jpg 90w\" sizes=\"auto, (max-width: 900px) 100vw, 900px\" \/><\/p>\n<p>Las primeras dosis de una vacuna contra el sida con tecnolog\u00eda de ARN mensajero fueron administradas a humanos, seg\u00fan anunciaron el jueves la empresa biotecnol\u00f3gica estadounidense Moderna y la Iniciativa Internacional para la Vacuna contra el Sida.<\/p>\n<p>El llamado ensayo de fase 1 se lleva a cabo en Estados Unidos en 56 adultos sanos y sin VIH.<\/p>\n<p>A pesar de cuatro d\u00e9cadas de investigaci\u00f3n, los cient\u00edficos a\u00fan no desarrollaron una vacuna contra esta enfermedad que mata a cientos de miles de personas cada a\u00f1o.<\/p>\n<p>Sin embargo, los recientes \u00e9xitos de la tecnolog\u00eda de ARN mensajero, que permiti\u00f3 el desarrollo de vacunas Covid-19 en un tiempo r\u00e9cord, incluida la de Moderna, suscit\u00f3 esperanzas, inform\u00f3 la agencia AFP.<\/p>\n<p>El objetivo de la vacuna que se est\u00e1 probando es estimular la producci\u00f3n de un determinado tipo de anticuerpos (bnAb), capaces de actuar contra las numerosas variantes circulantes del VIH, el virus que causa el sida.<\/p>\n<p>La vacuna pretende educar a las c\u00e9lulas B, que forman parte de nuestro sistema inmunitario, para que produzcan estos anticuerpos.<\/p>\n<figure class=\"mb-3\"><img decoding=\"async\" src=\"https:\/\/www.telam.com.ar\/thumbs\/bluesteel\/advf\/imagenes\/2018\/05\/5b02f232ed05d_900.jpg\" alt=\"Test HIV VIH SIDA AIDS Foto Archivo\" width=\"100%\" height=\"100%\" \/><\/p>\n<div class=\"media-icons\"><\/div><figcaption>Test HIV VIH SIDA AIDS. Foto Archivo<\/figcaption><\/figure>\n<p>Para ello, el ensayo probar\u00e1 la inyecci\u00f3n de un inmun\u00f3geno inicial, es decir, una sustancia capaz de provocar una respuesta inmunitaria, y un inmun\u00f3geno de refuerzo inyectado posteriormente.<\/p>\n<p>&#8220;La producci\u00f3n de bnAbs est\u00e1 ampliamente considerada como un objetivo de la vacunaci\u00f3n contra el VIH, y este es un primer paso en ese proceso&#8221;, indicaron en el comunicado.<\/p>\n<p>David Diemert, cient\u00edfico jefe del ensayo en uno de los cuatro centros donde \u00e9ste se realiza, la Universidad George Washington, afirm\u00f3 que &#8220;ser\u00e1n necesarios otros inmun\u00f3genos para guiar al sistema inmunitario por el camino correcto, pero esta combinaci\u00f3n de un refuerzo y un potenciador podr\u00eda ser el primer componente clave de un posible r\u00e9gimen de vacunas contra el VIH&#8221;.<\/p>\n<p>Los inmun\u00f3genos utilizados fueron desarrollados por la organizaci\u00f3n de investigaci\u00f3n cient\u00edfica Iniciativa Internacional para la Vacuna contra el Sida (IAVI) y el Instituto de Investigaci\u00f3n Scripps, con el apoyo de la Fundaci\u00f3n Bill y Melinda Gates, el Instituto Nacional de Enfermedades Infecciosas (NIAD) de Estados Unidos, y Moderna.<\/p>\n<figure class=\"mb-3\"><img decoding=\"async\" src=\"https:\/\/www.telam.com.ar\/thumbs\/bluesteel\/advf\/imagenes\/2016\/12\/58404faecf9fd_900.jpg\" alt=\"Test HIV VIH SIDA AIDS Foto Archivo\" width=\"100%\" height=\"100%\" \/><\/p>\n<div class=\"media-icons\"><\/div><figcaption>Test HIV VIH SIDA AIDS. Foto Archivo<\/figcaption><\/figure>\n<p>El a\u00f1o pasado, un primer ensayo, en el que no se utiliz\u00f3 el ARN mensajero, sino que prob\u00f3 el primer inmun\u00f3geno, demostr\u00f3 que se obtuvo la respuesta inmunitaria deseada en varias docenas de participantes.<\/p>\n<p>El siguiente paso fue colaborar con Moderna.<\/p>\n<p>&#8220;Dada la rapidez con la que se pueden producir las vacunas de ARN mensajero, esta plataforma ofrece un enfoque m\u00e1s flexible y receptivo a la hora de probar y dise\u00f1ar una vacuna&#8221;, se\u00f1al\u00f3 el texto.<\/p>\n<p>Mark Feinberg, director de la IAVI, dijo que &#8220;la b\u00fasqueda de una vacuna contra el VIH es larga y dif\u00edcil, y contar con nuevas herramientas en t\u00e9rminos de inmun\u00f3genos y plataforma podr\u00eda resultar clave para avanzar r\u00e1pidamente&#8221;.<\/p>\n","protected":false},"excerpt":{"rendered":"<div class=\"post-excerpt\"><p>El ensayo busca estimular la producci\u00f3n de un determinado tipo de anticuerpos (bnAb), capaces de actuar contra las numerosas variantes circulantes del virus.\u00a0El reciente \u00e9xito de la tecnolog\u00eda de ARN mensajero en la lucha contra el Covid-19 en tiempo r\u00e9cord suscit\u00f3 esperanzas, aunque en cuatro d\u00e9cadas de investigaci\u00f3n no se haya logrado a\u00fan una vacuna<\/p>\n<\/div>","protected":false},"author":2,"featured_media":36135,"comment_status":"closed","ping_status":"closed","sticky":false,"template":"","format":"standard","meta":{"_acf_changed":false,"footnotes":""},"categories":[2],"tags":[],"class_list":["post-36134","post","type-post","status-publish","format-standard","has-post-thumbnail","hentry","category-noticias"],"acf":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v28.1 - 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